Interaction of tea catechins with lipid bilayers investigated with liposome systems.
نویسندگان
چکیده
Interaction of tea catechins with lipid bilayers was investigated with liposome systems, which enabled us to separate liposomes from the external medium by centrifugation. We found that epicatechin gallate had the highest affinity for lipid bilayers, followed by epigallocatechin gallate, epicatechin, and epigallocatechin. Epicatechin gallate and epigallocatechin gallate in the surface of lipid bilayer perturbed the membrane structure.
منابع مشابه
Effects of external factors on the interaction of tea catechins with lipid bilayers.
Green tea contains a high concentration of such catechins as (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg). Their biological activities have been evaluated by in vitro experiments using cultured cells or bacteria, but the order of activity of the various catechins differed with the study. We have been studying the intera...
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 63 12 شماره
صفحات -
تاریخ انتشار 1999